The AskBio AAV technology platform

Since our founding over 20 years ago and with more than 40 years of pioneering AAV research, our vision has always extended beyond therapeutic development. Making genetic medicines that appropriately target the right cells, and provide benefit to patients in a safe manner is vital to improving patient lives, and the science behind identifying and treating genetic disorders has greatly evolved.  

Equally important is helping to ensure that patients in need have access to genetic medicine.  It is why we consider our AAV technology platform one of our greatest innovations. Its components are shaping how we scale gene therapy manufacturing and lower production cost. 

It is this uncompromised vision that propelled the emergence of our gene therapy technology platform.

AAVPlatform proven end-to-end capability results in technology to increase scale and lower costs of goods as well as translate into clinic faster, safer and with greater predictability.

Three essential components of the AskBio AAV platform

Capsids

A vast range of capsid pool designed to match a variety of tropism and maximize transduction

Promoters

An expression cassette with gene control, regulation and inducible technology

Production

Pro10™ is a high-yield suspension cell line that increases overall therapeutic output and lowers production cost

dna

Cracking the code: Fast and scalable production of DNA

AskBio and TAAV Biomanufacturing Solutions are helping to revolutionize production DNA with a plasmid alternative that may be safer for patients due to the lack of animal origin materials and lowers production cost of AAV therapeutics.

The dawning of enzymatic DNA »

GMP manufacturing

Clinical and commercial GMP manufacturing

Our extensive manufacturing facilities in San Sebastian, Spain, allow for high-yield output of AAV vectors and for the production of neDNA™, a benchtop alternative to plasmid DNA.

Advance AAV production »

genetic researcher

Are you on the verge of the next great discovery?

Collaboration with researchers in leading institutions, bioscience organizations and patient advocacy programs is hard coded into our DNA.

Accelerate genetic discovery »